FABP4 and rheumatoid arthritis: In addition, BMS309403 (a FABP4 inhibitor) reduces inflammation and angiogenesis in diabetes and atherosclerosis.12 Previous studies have reported that M1-polarized macrophages in the synovium promote inflammation and angiogenesis in RA;13 however, the secretion of FABP4 by synovial macrophages and its role in RA progression remain unclear.