ATG7 and neoplasm: Karsli–Uzunbas et al. used KrasG12D- and Trp53−/−-driven murine lung cancer models and showed that the conditional knockout of Atg7 in the whole body (in host and cancer cells) leads to the substantial regression of established tumors, which, surprisingly, was even greater than Atg7-knockout in cancer cells alone, suggesting that both host autophagy and tumor-specific autophagy support tumor growth [26].