Interestingly, KRAS mutations happen to be more common in colorectal serrated adenocarcinoma that involves the NF-kB pathway and the secretion of IL-8 which may account for the association of the higher abundance of Faecalibacterium in KRAS mutated CRC patients [30, 31]. Here, NFKB1 is linked to colorectal serrated adenocarcinoma.