The Endogenous Hormones, Nutritional Biomarkers and Prostate Cancer Collaborative Group (EHNBPCCG) is a pooled individual participant nested case-control dataset of prospective studies of hormonal and nutritional factors and prostate cancer risk, which previously reported positive associations of IGF-I, IGF-II, IGFBP-2 and IGFBP-3 with overall prostate cancer risk and an inverse association with IGFBP-1.8 The gene discussed is IGF2; the disease is Familial prostate cancer.