IGFBP-1 was inversely associated with overall prostate cancer (0.95: 0.91, 0.99; P = 0.03), and IGFBP-2 was not associated with prostate cancer risk (0.98: 0.93, 1.03; P = 0.46) (Figure 1). Here, IGFBP2 is linked to prostate cancer.