Univariate analysis of clinicopathological characteristics and OS of the patients in TCGA ccRCC cohort showed that age, grade, stage, T, M, and TRIB3 expression were significantly correlated with OS (P < 0.001; Table 3), and age, grade, stage, and TRIB3 expression remained significantly associated with OS in multivariate analysis (Figure 2(c), p < 0.05). The gene discussed is TRIB3; the disease is nonpapillary renal cell carcinoma.