Previous findings showed that hsa-miR-338-3p mediates a series of biological process associated with the etiology of GDM, such as gluconeogenesis, hepatic insulin resistance, and vascular endothelial cells apoptosis, by targeting distinct genes, including HIF-1α, AATK, PTIP, and PP4R1 [41–44]. The gene discussed is INS; the disease is gestational diabetes.