In the context of disease, dysfunction or dysregulation of AR is known to be associated in causing multiple diseases (Matsumoto et al., 2013), including androgen insensitivity syndrome (Bevan et al., 1997), prostate cancer (Huang and Tindall, 2002), and SBMA (Suzuki et al., 2008; Beitel et al., 2013). The gene discussed is AR; the disease is Kennedy disease.