ADAM19 and cancer: Implicated genes include BTG2 in lymphoma, which is involved in the regulation of the G1/S transition of the cell cycle and has recently been implicated as a driver of blood cancers based on mutations in its coding sequence10, and ADAM19 in hemopoietic tumors, which has been implicated in the oncogenesis of breast42, prostate43, colorectal44 and ovarian45 cancers.