In a validation cohort (validation cohort II, Supplementary Table S5), the expression of CLEC3B was significantly upregulated in ASCs freshly isolated from the adipose tissues (passage 0-ASCs) of the lymphedema group (n = 3) versus the healthy group (n = 3) (Supplementary Fig. S13b; q value = 0.026, differential expression test). This evidence concerns the gene CLEC3B and lymphedema.