CLEC3B and lymphedema: In addition, significantly upregulated expression of CLEC3B was observed in cultured ASCs (passage 3) from the lymphedema versus normal adipose tissues of patients with secondary lymphedema (n = 8) based on the bulk RNA-seq data previously generated by our lab45 (Supplementary Fig. S13c; P value = 0.024, Wilcoxon signed-rank test).