Notably, c3, a lymphedema-associated ASC subpopulation that was significantly expanded in SVF (Fig. 2c) and the ASC lineage (Supplementary Fig. S5a), showed high expression of DPP4 and CD55, two markers for multipotent interstitial progenitor cells in adipose tissues36 (Supplementary Fig. S4). This evidence concerns the gene C3 and lymphedema.