The top three drugs, i.e. Thioridazine, BRD-K16533489, and Pelitinib each has an overlap of 0.2857 with the reverse signature of CC and CXC chemokines in BC Furthermore, Pelitinib and Thioridazine may have a synergistic effect on restoring the gene expression pattern with an overlap of 0.4762. This evidence concerns the gene CXCR1 and breast cancer.