The results showed that the proportion of PMN-MDSCs (CD11b+ LY6G+ LY6Clow) in bone marrow, spleen and tumor tissue of BAFF KO tumor-bearing mice was significantly decreased compared with that in WT mice, while no significant difference was observed in M-MDSCs (CD11b+LY6G− LY6Chigh) [22] (Fig. 3i–k). This evidence concerns the gene TNFSF13B and neoplasm.