Circ_0002483 has been verified to inhibit NSCLC progression in vivo and in vitro, and increases NSCLC cell sensitivity to Taxol through sponging of miR-182-5p to inhibit expression of FOXO1, FOXO3 and GRB2 mRNAs [13]. The gene discussed is FOXO3; the disease is non-small cell lung carcinoma.