In addition, we also provided evidence that the cumulative survival of SKCM patients significantly improves when a higher expression of the TGM2 gene is associated with a stronger infiltration of CD8 + T cells (Fig. 6d), Neutrophils (Fig. 6e), and Dendritic Cells (Fig. 6g), compared to the increase in tumor-infiltrating immune cells alone. The gene discussed is TGM2; the disease is neoplasm.