In this study, we decided to investigate the antitumor effects of SS on breast tumors of spontaneous mouse mammary tumor (SMMT) mice models injected with SS, as well as evaluate its effect on tumor size, the anti-apoptotic genes B-cell lymphoma-extra-large (Bcl-xl) and B-cell lymphoma 2(Bcl2) and apoptosis. Here, BCL2 is linked to breast neoplasm.