VEGFA and diabetic macular edema: Anti-VEGF is extensively applied in the field of ophthalmology for indications that include exudative age-related macular degeneration (AMD), diabetic macular edema (DME), polypoidal choroidal vasculopathy (PCV), retinal vein occlusions (RVO), myopic choroid neovascularization (mCNV) and retinopathy of prematurity [7–9].