DGCR8 and toxic multinodular goitre: More recently, a study identified a germline variant in exon 7 of DGCR8 (NM_022720.6:c.1552G>A; p.Glu518Lys) in all affected members of a family with both euthyroid multinodular goiter (MNG) and schwannomatosis (Rivera et al., 2020).