Future efforts to find novel PVs for schwannomatosis might be greatly aided by a similar approach to the one used by Piotrowski and colleagues, which involved deep sequencing of the full gene region of NF2, SMARCB1 and LZTR1, which will help detect noncoding PVs that are difficult to identify by standard NGS panels or WES. Here, SMARCB1 is linked to schwannomatosis.