The genetic architecture of non‐NF2‐related schwannomatosis appears to be more complex than that of NF1 and NF2‐related schwannomatosis with constitutional SMARCB1 PVs contributing in much higher proportion to familial schwannomatosis than they do to sporadic cases, whereas germline LZTR1 PVs seem to contribute similarly to familial and sporadic cases (Evans et al., 2018). The gene discussed is LZTR1; the disease is schwannomatosis.