AKT1 and lung adenocarcinoma: A previous study reported that miR-1290 was upregulated in tissues and serum samples from patients with lung adenocarcinoma and correlated with poor prognosis, and suppressor of cytokine signaling 4 (SOCS4) was target of miR-1290, by targeting SOCS4, miR-1290 facilitated the JAK/STAT3 and PI3K/AKT pathways [24].