Nevertheless, there were 6 genes that showed a greater than −1.25-fold decrease in the CKD dogs when compared to the control dogs including CCL4 (−1.34), CSF1 (−1.39), CX3CL1 (−1.26), IL-7 (−1.51), CXCR5 (−1.55), and FASLG (−1.29) (Figure 3). Here, CCL4 is linked to chronic kidney disease.