GRIN2B and COVID-19: We suggested that the six antihistamines (Loratadine, Fexofenadine, Triprolidine, Ebastine, Dimetindene, and Terfenadine) played a critical role in COVID-19 by affecting the GRIN2B target as well as inhibiting neuroactive ligand–receptor interaction (KEGG ID: hsa04080).