In the CP group, APC (30%; 9 out of 30 CP cases carrying somatic mutations), TP53 (17%; 5/30), BRAF (10%; 3/30), FGFR3 (10%; 3/30), KRAS (10%; 3/30), and POLE (10%; 3/30) were the most mutated genes, while TP53 (62%; 5 out of 8 IBD cases carrying somatic mutations), APC (37%; 3/8), and POLE (25%; 2/8) were the most mutated ones in the IBD group. The gene discussed is APC; the disease is inflammatory bowel disease.