The polymorphism of ERCC1/XPF [2] genes encoding for proteins that are involved in DNA repair processes and LIN28A [3], which is important in the control of cell proliferation, were associated with increased neuroblastoma risk, and FABP4 [4]-mediated macrophages may increase the characteristics of proliferation and migration in neuroblastoma cells by promoting tumor progression by indirectly altering angiogenesis, matrix metalloproteinases (MMP) activity, and cytokine production [5]. This evidence concerns the gene ERCC4 and neuroblastoma.