CD274 and non-small cell lung carcinoma: In all, we firstly demonstrated that circ_0092012 knockdown could suppress tumor-autonomous malignant phenotypes and immune escape by miR-635/PDL1 axis in NSCLC, which provided new insights into the action pattern of circ_0092012 in NSCLC tumorigenesis and progression and the promising therapeutic targets for the development of RNA-based therapy in NSCLC patients.