NLRP3 and Parkinson disease: In N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced PD mice, salidroside inhibited thioredoxin-interacting protein/NLRP3/caspase-1 signaling by suppressing the pathway, thereby inhibiting neuronal pyroptosis and neuroinflammation (Zhang X. et al., 2020).