In, Sevilla et al. (2016) identified for the first time a rare form of axonal Charcot-Marie-Tooth disease (CMT2Z; OMIM: 616688) related to a mutation in the MORC2 gene (NM_001303256.3; c.754 C > T; p.R252W) with autosomal dominant segregation in a Spanish family. Here, MORC2 is linked to Charcot-Marie-Tooth disease.