SLC1A2 and Cognitive impairment: In addition, EAAT2/Glt-1 polymorphisms and mutations have been associated with cognitive defects in schizophrenia (Spangaro et al., 2014, 2018; Fiorentino et al., 2015; Mazza et al., 2019) and an increased risk for autism (Autism Genome Project Consortium, Szatmari et al., 2007; Xu et al., 2008), respectively.