According to the proportions of each vertical setting as shown in Sankey diagram, luteolin mosloflavone I and mosloflavone II played a central role in the protection of MSTF on the IAV-induced lung inflammation in mice mostly through inhibiting pathways in cancer, MAPK signaling pathway, lipid and atherosclerosis, and chemical carcinogenesis ROS by targeting MAPK14, JAK2/3, HSP90, and HRAS, indicating the anti-inflammatory mechanism of MSTF. This evidence concerns the gene MAPK14 and cancer.