We also performed KEGG pathway analysis (Figure 6(c)) and found that the TGF-β signalling pathway, ECM-receptor interaction, proteoglycans in cancer, and protein processing in endoplasmic reticulum, as well as the PI3K-AKT signalling pathway and the TNF signalling pathway, were activated in most cells, particularly fibroblasts. This evidence concerns the gene AKT1 and cancer.