After adjusting for age, gender, weight, cyanotic heart disease, preoperative Hb, CPB duration, and intraoperative RBC consumption, AID was an independent risk factor for postoperative RBC transfusion (OR 1.837, 95% CI 1.016–3.321, p = 0.044; Table 6). The gene discussed is GSTM1; the disease is heart disorder.