SPP1 and congenital bilateral aplasia of vas deferens from CFTR mutation: To further explain the regulatory network and molecular mechanisms of CAVD, we filtered 10 hub genes (SPP1, TREM1, GPM6A, CCL19, CR1, NCAM1, CNTN1, TLR8, SDC1, and COL6A6), constructed the LncRNA-miRNA-mRNA network, and calculated the correlation between hub genes and immune cell infiltration, which has not been reported previously.