Table 4 lists the enriched GO terms of these rule genes. It was indicated that most rules are shown to be associated with ribosome-associated biological processes. According to recent publications, ribosome-associated biological processes have been widely shown to be associated with the pathogenesis of T2D. In 2019, in a metabolic study on pancreatic tissues, ribosome-associated genes have been shown to participate in the ERK/hnRNPK/DDX3X pathway in pancreatic islet cells and further regulated the initiation and progression of T2D (Good et al., 2019), consistent with our results. The gene discussed is DDX3X; the disease is type 2 diabetes mellitus.