As shown in Table 4, univariate COX regression analysis indicated CVD (P < 0.001), gender (P < 0.001), age (P < 0.001), SBP (P=0.001), BMI(P=0.038), monocyte (P=0.001), erythrocyte (P=0.027), RDW (P < 0.001), CRP (P=0.037), albumin (P=0.001), ALP (P=0.005), BUN (P < 0.001), LDH (P < 0.001), UA (P < 0.001), creatinine (P < 0.001), osmolality (P < 0.001), HbA1c (P=0.027), HDL (P=0.021), NLR (P < 0.001), LMR (P < 0.001), and SIRI (P < 0.001) affected the prognosis of COPD. This evidence concerns the gene ALB and chronic obstructive pulmonary disease.