KEGG pathways analysis suggested that compared with the db/dm mice microglia, the enrichment items of the db/db mice microglia were mainly concentrated in infection- and inflammation-associated pathways, such as pathways in Coronavirus disease-COVID-19, Epstein-Barr virus infection, phagosome and NF-κB signaling pathway (Figure 6A; Supplementary Table 3). The gene discussed is NFKB1; the disease is Epstein-Barr virus infection.