Predictors of poor outcome in COVID-19 patients receiving TCZ, according to studies conducted globally, include older age, comorbidities such as hypertension, diabetes mellitus, and immunosuppression, days from diagnosis until TCZ administration, elevated C-reactive protein (CRP), lactate dehydrogenase (LDH), troponin I, and neutrophil levels [15–17]. The gene discussed is CRP; the disease is COVID-19.