However, through immunohistochemical analysis, Mazur et al. (Mazur et al., 2010) identified NRF2 expression in both nuclear compartments of proliferative alveolar epithelial and alveolar epithelial type II cells of IPF patients, but not in the fibroblasts, indicating that NRF2 expression varies between cell types. Here, NFE2L2 is linked to idiopathic pulmonary fibrosis.