Salvianolic acid B is an organic acid extracted from the Chinese medicine Salvia miltiorrhiza (Chen et al., 2014), which has been proven to regulate the differentiation of fibroblasts and modulate the downstream antioxidant genes of NRF2, consequently mitigating the progression of renal fibrosis (Lu et al., 2010). The gene discussed is NFE2L2; the disease is renal fibrosis.