Recently, studying the Galloway-Mowat syndrome (GAMOS), a condition associated with mutations in the TCTC complex subunits and characterized by microcephaly and early onset nephrotic syndrome (SRNS) (Braun et al., 2017; Edvardson et al., 2017), Braun et al. described that PRPK knockdown impairs actin dynamics and human podocyte migration (Braun et al., 2017). Here, TP53RK is linked to Galloway-Mowat syndrome.