To be noted, regarding the genes used to construct the stemness subtype predictor and prognostic signature, GAS1 (Li et al., 2016a), CHIT1 (Li et al., 2016b), COL10A1 (Patra et al., 2021), FABP4 (Wang et al., 2019), HOXC9 (Hu et al., 2019), INHBB (Yuan et al., 2020), and NKAIN4 (Jin et al., 2020) have been previously found to be associated with CRC development. Here, NKAIN4 is linked to colorectal carcinoma.