However, SEPs such as selenoprotein P (SELP), glutathione peroxidases (Jameson & Diamond, 2004), thioredoxin reductases (TXNRD) and selenoprotein F (SEP15) have been shown to be able to regulate tumorigenesis through impacting cancer-related signaling proteins (Jia et al., 2020). Here, SELENOF is linked to cancer.