DYNC1LI1 and neoplasm: It controls protein synthesis by upregulating the rRNA levels through direct phosphorylation of RNA and spliceosomal machinery and targets a large variety of cytoskeletal and motor proteins, such as myosin-1, X, XVIIIa, Dynactin, Cytoplasmic Dynein Light Intermediate Chain 1 (LIC1), capping protein, Gelsolin, Septin, etc. It reduces the death/survival ratio, favours angiogenesis, and inactivates tumour suppressors in cancerous tissue.