PIM1 and hepatocellular carcinoma: The cytotoxicity of Pim was examined by MTT conversion assay, which was conducted in various HepG2 hepatoma-derived cell lines including HepG2.2.15 (Figure 2B), HepG2-NTCP (Figure 2C) and HepAD38, primary human hepatocytes (Figure 2D) and HCC cell line Huh-7 (Supplementary Figure S2).