In D-galactose and Aβ25-35-induced AD rats, different doses of MO also significantly increased the antioxidant enzyme activities (SOD, GSH-Px, and CAT), neurotransmitter levels (acetylcholine, gamma-aminobutyric, and dopamine), energy metabolism (Na+/K+-ATPsae), and relative synaptophysin expression levels (Deng et al., 2020). Here, SOD1 is linked to Alzheimer disease.