It has been reported that pulmonary fibrosis in animal models can be attenuated by knocking out genes encoding chemokines or neutralizing chemokines with antibodies [CCL2-CCR2 (Moore et al., 2001; Murray et al., 2008; Phan et al., 2021), CCL11-CCR3 (Huaux et al., 2005), CCL17 (Agostini and Gurrieri, 2006), CCL21-CCR7 (Habiel and Hogaboam, 2014), CCL22 (Strieter, 2005), CXCL6 (Besnard et al., 2013), CXCL12 (Phillips et al., 2004), CXCL14 (Li et al., 2019), CX3CL1-CX3CR1 (Rivas-Fuentes et al., 2020), CCR5 (Ishida et al., 2007)]. This evidence concerns the gene CXCL12 and pulmonary fibrosis.