MAPT and Alzheimer disease: Thus, Lewy bodies and α-synuclein in PD, β-amyloid peptides, and phosphorylated tau/tau proteins are common in AD (Duong and Gallagher, 1994; Elobeid et al., 2016), superoxide dismutase in ALS (Durham et al., 1997) and mutant huntingtin in HD (Scherzinger et al., 1997).