GGPS1 and plasma cell myeloma: Lacbay et al. (2018) reported the synthesis of a new category of thienopyrimidine-based bisphosphonate (ThP-BP) inhibitors 52–58 of the human geranylgeranyl pyrophosphate synthase (hGGPPS) that block protein prenylation in multiple myeloma (MM) cells leading to cellular apoptosis.