Pooled data from the 2 pivotal multicenter phase II studies of alectinib (NP28761 and NP28673) [7, 8] in ALK+ NSCLC patients who had progressed on, or were intolerant to, crizotinib, confirmed the efficacy of alectinib over long follow-up periods [9]. Here, ALK is linked to non-small cell lung carcinoma.