However, SS has clear genetic pathological characteristics, and more than 95% of patients have a characteristic chromosomal translocation (X; 18) (p11.2; q11.2) involving genes SS 18 and synovial sarcoma X chromosome breakpoint (SSX1, SSX2, SSX4), form an SS 18-SSX fusion gene, and then generate a variety of SS18-SSX fusion proteins [9], which can be detected by traditional cytogenetic FISH and RT-PCR methods. The gene discussed is SSX1; the disease is synovial sarcoma.