PTHLH and neoplasm: Furthermore, the phenotypic differences that distinguish CSCs and the non‐CSCs that comprise the bulk of tumor cells now appear to be consequent to the induction of EMT in CSCs.(17) The implications are important because this suggests that CSCs are tumor cells that acquire stem cell‐like properties as a consequence of a regulatable EMT(74) and we show here that PTHrP plays a crucial role in this process.