We also checked for modulation of the TGF-β1/2 expression in response to FAT1 knockdown in representative cell lines of glioma and other cancers such as U87MG (GBM), HeLa (cervical cancer), Panc-1 (pancreatic cancer), and HepG2 (hepatocellular cancer). This evidence concerns the gene FAT1 and familial pancreatic carcinoma.