When IL-10, ARG1, and iNOS expression in MDSCs was compared with that in monocytes, fold-change expression of ARG1 and iNOS was found significantly increased in sepsis MDSCs (p = 0.043 and p = 0.045) compared to sepsis monocytes but has no difference in IL-10 expression (Figure 3A). The gene discussed is NOS2; the disease is Sepsis.