Furthermore, it was observed that in the presence of Th17-proliferating conditions [in presence of recombinant TGF-β (5 ng/ml) and IL-6 (20 ng/ml)], MDSCs induce more CD4+FOXP3+ expression on T cells (p = 0.043) in sepsis patients, while IL-17 producing T cells were minimal in disease condition compared to that in HCs (p = 0.031) (Figure 3E). The gene discussed is TGFB1; the disease is Sepsis.