CCL5 and juvenile idiopathic arthritis: However, in juvenile idiopathic arthritis (JIA) isolated synovial CD8 T cells were found to rapidly release high levels of CCL5 upon TCR stimulation, without new protein synthesis, and synovial CD8 T cells showed high levels of CCL5 protein and increased CCL5 mRNA as compared to CD8 T cells from peripheral blood (38).