ADM and diabetes mellitus: The median adrenomedullin mRNA level in patients with DM was 0.047 (0.026-0.112), which was significantly higher than that in IMNM patients (0.020 [0.004-0.036], p = 0.022) and HCs (0.011 [0.004-0.025], p < 0.001) (Figure 2A).